Skin tumors Rb(eing) uncovered

The Rb1 gene was the first bona fide tumor suppressor identified and cloned more than 25 years ago. Since then, a plethora of studies have revealed the functions of pRb and the existence of a sophisticated and strictly regulated pathway that modulates such functional roles. An emerging paradox affec...

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Bibliographic Details
Main Authors: CLOTILDE eCOSTA, Jesus M Paramio, MIRENTXU eSANTOS
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Oncology
Subjects:
pRb
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00307/full