The biomechanical properties of an epithelial tissue determine the location of its vasculature
Vasculature is denser in soft than in stiff tissues. Kragl et al. suggest a mechanistic link between biomechanical tissue properties and vascularization by showing that integrin-linked kinase reduces the contractile forces of the cell cortex in endocrine pancreatic cells, facilitating their adhesion...
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Bibliographic Details
| Main Authors: |
Martin Kragl,
Rajib Schubert,
Haiko Karsjens,
Silke Otter,
Barbara Bartosinska,
Kay Jeruschke,
Jürgen Weiss,
Chunguang Chen,
David Alsteens,
Oliver Kuss,
Stephan Speier,
Daniel Eberhard,
Daniel J. Müller,
Eckhard Lammert |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2016-12-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/ncomms13560
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