Regulation of multidrug resistance by microRNAs in anti-cancer therapy
Multidrug resistance (MDR) remains a major clinical obstacle to successful cancer treatment. Although diverse mechanisms of MDR have been well elucidated, such as dysregulation of drugs transporters, defects of apoptosis and autophagy machinery, alterations of drug metabolism and drug targets, disru...
Main Authors: | Xin An, Cesar Sarmiento, Tao Tan, Hua Zhu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-01-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383516300934 |
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