Research advances in pharmacological prevention of pancreatitis after endoscopic retrograde cholangiopancreatography

• Main Authors: WANG Ai, ZHAO Lijin
• Format: Article
• Language: zho
• Published: Editorial Department of Journal of Clinical Hepatology 2017-01-01
• Series: Linchuang Gandanbing Zazhi
• Online Access: http://www.lcgdbzz.org/qk_content.asp?id=7967

Endoscopic retrograde cholangiopancreatography (ERCP) has become an important method for the diagnosis and treatment of cholangio-pancreatic duct diseases. Post-ERCP pancreatitis (PEP) is the most common complication and its incidence has increased up to 40% in recent years. The prevention of PEP has always been a hot topic in clinical research. This article reviews the research advances in the pharmacological prevention of PEP and points out that controlled clinical trials with a large sample size are still needed to investigate the effect of preventive drugs, and further studies should focus on optimal medication time, route of administration, and dose. In addition, demographic features of populations from different countries and different age groups should be taken into consideration.