Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation

<p>Abstract</p> <p>Background</p> <p>Liver-to-pancreas conversion offers new possibilities for β-cell engineering for type 1 diabetes therapy. Among conceivable sources of liver cells, we focused on BMEL cells. These untransformed mouse embryonic liver cells have been r...

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Bibliographic Details
Main Authors: Martignat Lionel, Delisle Juliette, Bach Jean-Marie, Bösch Steffi, Louzier Vanessa
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/1/136