Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation
<p>Abstract</p> <p>Background</p> <p>Liver-to-pancreas conversion offers new possibilities for β-cell engineering for type 1 diabetes therapy. Among conceivable sources of liver cells, we focused on BMEL cells. These untransformed mouse embryonic liver cells have been r...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-12-01
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Series: | BMC Research Notes |
Online Access: | http://www.biomedcentral.com/1756-0500/1/136 |