Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion

To trigger gamete fusion, spermatozoa need to activate the molecular machinery in which sperm IZUMO1 and oocyte JUNO (IZUMO1R) interaction plays a critical role in mammals. Although a set of factors involved in this process has recently been identified, no common factor that can function in both ver...

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Bibliographic Details
Main Authors: Naokazu Inoue, Yoshihisa Hagihara, Ikuo Wada
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/66313