The proinflammatory RAGE/NF-κB pathway is involved in neuronal damage and reactive gliosis in a model of sleep apnea by intermittent hypoxia.

The proinflammatory RAGE/NF-κB pathway is involved in neuronal damage and reactive gliosis in a model of sleep apnea by intermittent hypoxia.

Sleep apnea (SA) causes long-lasting changes in neuronal circuitry, which persist even in patients successfully treated for the acute effects of the disease. Evidence obtained from the intermittent hypoxia (IH) experimental model of SA has shown neuronal death, impairment in learning and memory and...

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Bibliographic Details
Main Authors: Maria Florencia Angelo, Alejandra Aguirre, Rolando X Avilés Reyes, Alejandro Villarreal, Jerónimo Lukin, Matías Melendez, Virginia Vanasco, Phil Barker, Silvia Alvarez, Alberto Epstein, Diana Jerusalinsky, Alberto Javier Ramos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4180086?pdf=render

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http://europepmc.org/articles/PMC4180086?pdf=render

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