Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.

Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.

Translation is divided into initiation, elongation, termination and ribosome recycling. Earlier work implicated several eukaryotic initiation factors (eIFs) in ribosomal recycling in vitro. Here, we uncover roles for HCR1 and eIF3 in translation termination in vivo. A substantial proportion of eIF3,...

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Bibliographic Details
Main Authors: Petra Beznosková, Lucie Cuchalová, Susan Wagner, Christopher J Shoemaker, Stanislava Gunišová, Tobias von der Haar, Leoš Shivaya Valášek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3836723?pdf=render

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