Use of immunohistochemical analysis of CK5/6, CK14, and CK34betaE12 in the differential diagnosis of solid papillary carcinoma in situ from intraductal papilloma with usual ductal hyperplasia of the breast

Objectives: The aim of this study was to use immunohistochemistry to differentiate solid papillary carcinoma in situ from intraductal papilloma with usual ductal hyperplasia (IPUDH). Three types of high-molecular-weight cytokeratins (CKs) – CK5/6, CK14, and CK34betaE12 – were targeted. Methods: We s...

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Bibliographic Details
Main Authors: Ichiro Maeda, Shinya Tajima, Yoshihide Kanemaki, Koichiro Tsugawa, Masayuki Takagi
Format: Article
Language:English
Published: SAGE Publishing 2018-11-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/2050312118811542