Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles
Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivativeswere prepared by the reaction of nitrilimine with different dipolarophilic reagents. The newcompounds were characterized using IR, 1H-NMR, 13...
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| Language: | English |
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MDPI AG
2008-04-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/13/4/1011/ |
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doaj-384fc38e78f246bc960228d2300c11ce2020-11-24T21:05:39ZengMDPI AGMolecules1420-30492008-04-011341011102410.3390/molecules13041011Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some DipolarophilesOmar A. MiqdadNadia G. KandileHamdi M. HassaneenNada M. AbunadaSeveral 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivativeswere prepared by the reaction of nitrilimine with different dipolarophilic reagents. The newcompounds were characterized using IR, 1H-NMR, 13C-NMR and mass spectra. Biologicalscreening of some compounds is reported.http://www.mdpi.com/1420-3049/13/4/1011/Pyrazolinepyrrolo[34-c]pyrazole-46-dionenitriliminedipolarophilebiological activity |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Omar A. Miqdad Nadia G. Kandile Hamdi M. Hassaneen Nada M. Abunada |
| spellingShingle |
Omar A. Miqdad Nadia G. Kandile Hamdi M. Hassaneen Nada M. Abunada Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles Molecules Pyrazoline pyrrolo[3 4-c]pyrazole-4 6-dione nitrilimine dipolarophile biological activity |
| author_facet |
Omar A. Miqdad Nadia G. Kandile Hamdi M. Hassaneen Nada M. Abunada |
| author_sort |
Omar A. Miqdad |
| title |
Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles |
| title_short |
Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles |
| title_full |
Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles |
| title_fullStr |
Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles |
| title_full_unstemmed |
Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles |
| title_sort |
synthesis and biological activity of some new pyrazoline and pyrrolo[3,4-c]pyrazole-4,6-dione derivatives: reaction of nitrilimines with some dipolarophiles |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2008-04-01 |
| description |
Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivativeswere prepared by the reaction of nitrilimine with different dipolarophilic reagents. The newcompounds were characterized using IR, 1H-NMR, 13C-NMR and mass spectra. Biologicalscreening of some compounds is reported. |
| topic |
Pyrazoline pyrrolo[3 4-c]pyrazole-4 6-dione nitrilimine dipolarophile biological activity |
| url |
http://www.mdpi.com/1420-3049/13/4/1011/ |
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