Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles

Synthesis and Biological Activity of Some New Pyrazoline and Pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives: Reaction of Nitrilimines with Some Dipolarophiles

Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivativeswere prepared by the reaction of nitrilimine with different dipolarophilic reagents. The newcompounds were characterized using IR, 1H-NMR, 13...

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Bibliographic Details
Main Authors: Omar A. Miqdad, Nadia G. Kandile, Hamdi M. Hassaneen, Nada M. Abunada
Format: Article
Language:English
Published: MDPI AG 2008-04-01
Series:Molecules
Subjects:
Pyrazoline
pyrrolo[3
4-c]pyrazole-4
6-dione
nitrilimine
dipolarophile
biological activity
Online Access:http://www.mdpi.com/1420-3049/13/4/1011/
Description
Summary:Several 1,3-diaryl-5-(cyano-, aminocarbonyl- and ethoxycarbonyl-)-2-pyrazoline, pyrrolo[3,4-c]pyrazole-4,6-dione and 1,3,4,5-tetraaryl-2-pyrazoline derivativeswere prepared by the reaction of nitrilimine with different dipolarophilic reagents. The newcompounds were characterized using IR, 1H-NMR, 13C-NMR and mass spectra. Biologicalscreening of some compounds is reported.
ISSN:1420-3049

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