SLiM-Enrich: computational assessment of protein–protein interaction data as a source of domain-motif interactions

Many important cellular processes involve protein–protein interactions (PPIs) mediated by a Short Linear Motif (SLiM) in one protein interacting with a globular domain in another. Despite their significance, these domain-motif interactions (DMIs) are typically low affinity, which makes them challeng...

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Bibliographic Details
Main Authors: Sobia Idrees, Åsa Pérez-Bercoff, Richard J. Edwards
Format: Article
Language:English
Published: PeerJ Inc. 2018-10-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/5858.pdf