2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling

2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling

Abstract Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people every year and so far, there are no therapeutic cures available. Even though animal and histological models ha...

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Bibliographic Details
Main Authors: Eduarda G Z Centeno, Helena Cimarosti, Angela Bithell
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Molecular Neurodegeneration
Subjects:
Human induced pluripotent stem cells
Neurodegenerative disease
3D culture
Online Access:http://link.springer.com/article/10.1186/s13024-018-0258-4

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