Stable expression and potential use of West Nile virus envelope glycoproteins preM/E as antigen in diagnostic tests

Stable expression and potential use of West Nile virus envelope glycoproteins preM/E as antigen in diagnostic tests

West Nile virus (WNV) envelope glycoproteins preM/E were stably expressed in baby hamster kidney cells and tested as antigen in a fluorescent antibody assay for WNV antibodies. Sera from horses, mice and chicken immunized with an inactivated WNV vaccine and, less consistently, sera from horses acute...

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Bibliographic Details
Main Authors: Juliana Felipetto Cargnelutti, Mário Celso Sperotto Brum, Rudi Weiblen, Eduardo Furtado Flores
Format: Article
Language:English
Published: Sociedade Brasileira de Microbiologia 2011-09-01
Series:Brazilian Journal of Microbiology
Subjects:
West Nile virus
WNV
M/E glycoproteins
stable expression
diagnostic
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300040
Description
Summary:West Nile virus (WNV) envelope glycoproteins preM/E were stably expressed in baby hamster kidney cells and tested as antigen in a fluorescent antibody assay for WNV antibodies. Sera from horses, mice and chicken immunized with an inactivated WNV vaccine and, less consistently, sera from horses acutely infected with WNV, reacted specifically with viral antigens present in preM/E-expressing cells.
ISSN:1517-8382
1678-4405

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