Recurrent tibial intra-cortical osteosarcoma: a case report and review of the literature

• Main Authors: Sugandhavesa Nantawit, Settakorn Jongkolnee, Sivasomboon Chate, Leerapun Taninnit, Arpornchayanon Olarn, Pruksakorn Dumnoensun
• Format: Article
• Language: English
• Published: BMC 2011-03-01
• Series: Journal of Medical Case Reports
• Online Access: http://www.jmedicalcasereports.com/content/5/1/93

<p>Abstract</p> <p>Introduction</p> <p>Intra-cortical osteosarcoma is the rarest subtype of osseous-producing tumor. Most reported cases present a low-grade histology with slow progression and good oncological control after adequate treatment. In this report, we describe a case and review the literature to propose adequate treatment.</p> <p>Case presentation</p> <p>We present the case of a 21-year-old Thai woman who was thought to have an intra-cortical osteosarcoma of the right tibia. We performed a wide resection and reconstruction with bone transportation using an Ilizarov external fixator. The tumor recurred five years later at the same site with a similar histology. We performed a new resection and reconstruction by ankle arthrodesis with adjuvant chemotherapy. At the last follow-up, she had remained active and free from disease for seven years.</p> <p>Conclusion</p> <p>This case report of recurrent intra-cortical osteosarcoma describes an atypical presentation. The low-grade histology, adequate surgical margin and adjuvant chemotherapy of the recurrent lesion were favorable factors, and our patient has remained free of any tumor recurrence.</p>