Neuroprotective effects and mechanism of cognitive-enhancing choline analogs JWB 1-84-1 and JAY 2-22-33 in neuronal culture and Caenorhabditis elegans

<p>Abstract</p> <p>Background</p> <p>Our previous work indicated that novel analogs of choline have cytoprotective effects <it>in vitro </it>that might be useful in neurodegenerative conditions such as Alzheimer's disease (AD). Furthermore, two lead com...

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Bibliographic Details
Main Authors: Terry Alvin V, Beach J Warren, Adam Bao-Ling, Aboukhatwa Marwa, Keowkase Roongpetch, Buccafussco Jerry J, Luo Yuan
Format: Article
Language:English
Published: BMC 2010-12-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/5/1/59