Transfusion-related Acute Lung Injury: Report of Two Cases

Transfusion-related Acute Lung Injury: Report of Two Cases

Transfusion-related acute lung injury (TRALI) is a severe life-threatening complication of blood transfusion, characterized by acute lung injury developing within 2–6 h of transfusion. However, TRALI is difficult to diagnose, and the initial report or suspicion of TRALI depends on close collaboratio...

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Main Authors: Zuzana Čermáková, M. Kořístka, Š. Blahutová, J. Dvořáčková, R. Brát, I. Valkovský, R. Hrdličková
Format: Article
Language:English
Published: Karolinum Press 2012-01-01
Series:Prague Medical Report
Subjects:
Transfusion-related acute lung injury
Granulocyte antibodies
Blood products
Online Access:https://pmr.lf1.cuni.cz/113/4/0294/
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spelling doaj-3838929dfa6142aeaff5e2af0556ba6b2020-11-25T00:22:40ZengKarolinum PressPrague Medical Report1214-69942336-29362012-01-01113429429810.14712/23362936.2015.13Transfusion-related Acute Lung Injury: Report of Two CasesZuzana Čermáková0M. Kořístka1Š. Blahutová2J. Dvořáčková3R. Brát4I. Valkovský5R. Hrdličková61st Department of Medicine – Department of Hematology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Prague, Czech Republic; Faculty of Medicine, University of Ostrava, Ostrava, Czech RepublicBlood Centre, University Hospital Ostrava, Ostrava, Czech RepublicBlood Centre, University Hospital Ostrava, Ostrava, Czech RepublicFaculty of Medicine, University of Ostrava, Ostrava, Czech RepublicFaculty of Medicine, University of Ostrava, Ostrava, Czech RepublicFaculty of Medicine, University of Ostrava, Ostrava, Czech RepublicBlood Centre, University Hospital Ostrava, Ostrava, Czech RepublicTransfusion-related acute lung injury (TRALI) is a severe life-threatening complication of blood transfusion, characterized by acute lung injury developing within 2–6 h of transfusion. However, TRALI is difficult to diagnose, and the initial report or suspicion of TRALI depends on close collaboration between clinical departments and transfusion centres. A total of 17 adverse post-transfusion reactions were reported to the Blood Centre of the University Hospital Ostrava as suspected TRALI between 2005 and 2010. We report two cases of serious TRALI with different pathogenetic mechanisms.https://pmr.lf1.cuni.cz/113/4/0294/Transfusion-related acute lung injuryGranulocyte antibodiesBlood products
collection DOAJ
language English
format Article
sources DOAJ
author Zuzana Čermáková
M. Kořístka
Š. Blahutová
J. Dvořáčková
R. Brát
I. Valkovský
R. Hrdličková
spellingShingle Zuzana Čermáková
M. Kořístka
Š. Blahutová
J. Dvořáčková
R. Brát
I. Valkovský
R. Hrdličková
Transfusion-related Acute Lung Injury: Report of Two Cases
Prague Medical Report
Transfusion-related acute lung injury
Granulocyte antibodies
Blood products
author_facet Zuzana Čermáková
M. Kořístka
Š. Blahutová
J. Dvořáčková
R. Brát
I. Valkovský
R. Hrdličková
author_sort Zuzana Čermáková
title Transfusion-related Acute Lung Injury: Report of Two Cases
title_short Transfusion-related Acute Lung Injury: Report of Two Cases
title_full Transfusion-related Acute Lung Injury: Report of Two Cases
title_fullStr Transfusion-related Acute Lung Injury: Report of Two Cases
title_full_unstemmed Transfusion-related Acute Lung Injury: Report of Two Cases
title_sort transfusion-related acute lung injury: report of two cases
publisher Karolinum Press
series Prague Medical Report
issn 1214-6994
2336-2936
publishDate 2012-01-01
description Transfusion-related acute lung injury (TRALI) is a severe life-threatening complication of blood transfusion, characterized by acute lung injury developing within 2–6 h of transfusion. However, TRALI is difficult to diagnose, and the initial report or suspicion of TRALI depends on close collaboration between clinical departments and transfusion centres. A total of 17 adverse post-transfusion reactions were reported to the Blood Centre of the University Hospital Ostrava as suspected TRALI between 2005 and 2010. We report two cases of serious TRALI with different pathogenetic mechanisms.
topic Transfusion-related acute lung injury
Granulocyte antibodies
Blood products
url https://pmr.lf1.cuni.cz/113/4/0294/
work_keys_str_mv AT zuzanacermakova transfusionrelatedacutelunginjuryreportoftwocases
AT mkoristka transfusionrelatedacutelunginjuryreportoftwocases
AT sblahutova transfusionrelatedacutelunginjuryreportoftwocases
AT jdvorackova transfusionrelatedacutelunginjuryreportoftwocases
AT rbrat transfusionrelatedacutelunginjuryreportoftwocases
AT ivalkovsky transfusionrelatedacutelunginjuryreportoftwocases
AT rhrdlickova transfusionrelatedacutelunginjuryreportoftwocases
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