Radiofrequency transmyocardial revascularization in experiment

• Main Authors: A. I. Opherkin, S. V. Logvinov, Y. A. Pokushalov
• Format: Article
• Language: English
• Published: Siberian State Medical University (Tomsk) 2002-09-01
• Series: Bûlleten' Sibirskoj Mediciny
• Subjects: ischemic heart disease; transmyocardial revascularization; radiofrequency energy; laser
• Online Access: https://bulletin.tomsk.ru/jour/article/view/3996

Conducted benchmark analysis of influence to mechanical punctures, transmyocardial radiofrequency influence and lazer radiating on myocardium. Study is conducted on 284 rats. Transmyocardial revascularization (ТМR) was executed with use intramuscular needle, Nd:YAG lazer, radiofrequency generator with needle electrode. Study of vascular density and myocardial perfusion was conducted through 1, 2, 4 and 8 weeks. Maximum increasing vascular density was observed on 4 week. In groups with radiofrequency TMR and Nd:YAG TMR specific vascular volume is enlarged in 5 once (26,9 ± 1,9% and 22,2 ± 1,7%, accordingly; Р < 0,05) in contrast with the checking group (4,9 ± 1,6%). In the group with mechanical ТМР specific vascular volume is enlarged small (6,1 ± 1,3%). Increasing an accumulation 99mTc-myoview in the group with radiofrequency TMR occurred on 8 week by comparing with the checking group, it has formed 2,82 ± 0,31% (Р < 0,05) and 1,68 ± 0,21% accordingly. Conclusion: Analysis of vascular density points to alike efficiency of lazer and radiofrequency transmyocardial revascularization. Radiofrequency ТМR causes an increasing vascular density and improvement myocardial perfusion in ischemic myocardium.