Divergent Regulation of Myotube Formation and Gene Expression by E2 and EPA during In-Vitro Differentiation of C2C12 Myoblasts

Divergent Regulation of Myotube Formation and Gene Expression by E2 and EPA during In-Vitro Differentiation of C2C12 Myoblasts

Estrogen (E2) and polyunsaturated fatty acids (n-3PUFA) supplements independently support general wellbeing and enhance muscle regeneration in-vivo and myotube formation in-vitro. However, the combined effect of E2 and n-3PUFA on myoblast differentiation is not known. The purpose of the study was to...

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Bibliographic Details
Main Authors: Orly Lacham-Kaplan, Donny M. Camera, John A. Hawley
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
17β-estradiol
n-3pufa
eicosapentaenoic acid
transcriptome
c2c12
myogenesis
Online Access:https://www.mdpi.com/1422-0067/21/3/745

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