A gene-expression-based neural code for food abundance that modulates lifespan

A gene-expression-based neural code for food abundance that modulates lifespan

How the nervous system internally represents environmental food availability is poorly understood. Here, we show that quantitative information about food abundance is encoded by combinatorial neuron-specific gene-expression of conserved TGFβ and serotonin pathway components in Caenorhabditis elegans...

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Bibliographic Details
Main Authors: Eugeni V Entchev, Dhaval S Patel, Mei Zhan, Andrew J Steele, Hang Lu, QueeLim Ch'ng
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
neural code
dietary restriction
neural circuit
gene regulation
expression variability
Online Access:https://elifesciences.org/articles/06259

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