Gluco-incretins regulate beta-cell glucose competence by epigenetic silencing of Fxyd3 expression.

<h4>Background/aims</h4>Gluco-incretin hormones increase the glucose competence of pancreatic beta-cells by incompletely characterized mechanisms.<h4>Methods</h4>We searched for genes that were differentially expressed in islets from control and Glp1r-/-; Gipr-/- (dKO) mice,...

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Bibliographic Details
Main Authors: David Vallois, Guy Niederhäuser, Mark Ibberson, Vini Nagaraj, Lorella Marselli, Piero Marchetti, Jean-Yves Chatton, Bernard Thorens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25058609/pdf/?tool=EBI