Angelica dahurica Extracts Improve Glucose Tolerance through the Activation of GPR119.

G protein-coupled receptor (GPR) 119 is expressed in pancreatic β-cells and intestinal L cells, and is involved in glucose-stimulated insulin secretion and glucagon-like peptide-1 (GLP-1) release, respectively. Therefore, the development of GPR119 agonists is a potential treatment for type 2 diabete...

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Bibliographic Details
Main Authors: Eun-Young Park, Eung-Hwi Kim, Chul-Young Kim, Mi-Hwi Kim, Jin-Seung Choung, Yoon-Sin Oh, Hong-Sub Moon, Hee-Sook Jun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4938581?pdf=render

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