Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes

Glycosphingolipid (GSL) fatty acid strictly regulates verotoxin 1 (VT1) and the HIV adhesin, gp120 binding to globotriaosyl ceramide within Gb3/cholesterol detergent resistant membrane (DRM) vesicle constructs and in Gb3 water-air interface monolayers in a similar manner. VT2 bound Gb3/cholesterol v...

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Bibliographic Details
Main Authors: Radhia Mahfoud, Adam Manis, Clifford A. Lingwood
Format: Article
Language:English
Published: Elsevier 2009-09-01
Series:Journal of Lipid Research
Subjects:
DRM
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520307276