Solution Structures of PPARγ2/RXRα Complexes

Solution Structures of PPARγ2/RXRα Complexes

PPARγ is a key regulator of glucose homeostasis and insulin sensitization. PPARγ must heterodimerize with its dimeric partner, the retinoid X receptor (RXR), to bind DNA and associated coactivators such as p160 family members or PGC-1α to regulate gene networks. To understand how coactivators are re...

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Bibliographic Details
Main Authors:	Judit Osz, Maxim V. Pethoukhov, Serena Sirigu, Dmitri I. Svergun, Dino Moras, Natacha Rochel
Format:	Article
Language:	English
Published:	Hindawi Limited 2012-01-01
Series:	PPAR Research
Online Access:	http://dx.doi.org/10.1155/2012/701412

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