Inhibitory Effect of Astragalus Polysaccharides on Lipopolysaccharide-Induced TNF-a and IL-1β Production in THP-1 Cells

Inhibitory Effect of Astragalus Polysaccharides on Lipopolysaccharide-Induced TNF-a and IL-1β Production in THP-1 Cells

Astragalus polysaccharides (APS), one of main bioactive components in Astragalus membranaceus Bunge, has been reported to possess anti-inflammatory activities, but the molecular mechanisms behind this activity are largely unknown. This study aimed to investigate expression of inflammatory cytokines...

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Bibliographic Details
Main Authors: Aiping Lu, Cheng Lu, Li Xu, Jun Shu, Xiaojuan He
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Molecules
Subjects:
Astragalus polysaccharides
anti-inflammatory
macrophage
MAPK
NF-κB
Online Access:http://www.mdpi.com/1420-3049/17/3/3155/

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