Insights From the Genome Sequence of Mycobacterium paragordonae, a Potential Novel Live Vaccine for Preventing Mycobacterial Infections: The Putative Role of Type VII Secretion Systems for an Intracellular Lifestyle Within Free-Living Environmental Predators

Insights From the Genome Sequence of Mycobacterium paragordonae, a Potential Novel Live Vaccine for Preventing Mycobacterial Infections: The Putative Role of Type VII Secretion Systems for an Intracellular Lifestyle Within Free-Living Environmental Predators

Mycobacterium paragordonae (Mpg) is a temperature-sensitive Mycobacterium species that can grow at permissive temperatures but fails to grow above 37°C. Due to this unique growth trait, Mpg has recently been proposed as a novel live vaccine candidate for the prevention of mycobacterial infections. F...

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Bibliographic Details
Main Authors: Byoung-Jun Kim, Ga-Yeong Cha, Bo-Ram Kim, Yoon-Hoh Kook, Bum-Joon Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium paragordonae
genome sequence
lateral gene transfer
Type VII secretion systems
M. gordonae
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01524/full

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