Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology

Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanism...

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Main Authors:	Olvera-Montaño Cecilia, Castellanos-González José Alberto, Navarro-Partida José, Cardona-Muñoz Ernesto Germán, López-Contreras Ana Karen, Roman-Pintos Luis Miguel, Robles-Rivera Ricardo Raúl, Rodríguez-Carrizalez Adolfo Daniel
Format:	Article
Language:	English
Published:	Hindawi Limited 2019-01-01
Series:	Journal of Diabetes Research
Online Access:	http://dx.doi.org/10.1155/2019/8562408

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spelling	doaj-37b59bf8ab1942468bf371d581bbb8522020-11-24T21:41:40ZengHindawi LimitedJournal of Diabetes Research2314-67452314-67532019-01-01201910.1155/2019/85624088562408Oxidative Stress as the Main Target in Diabetic Retinopathy PathophysiologyOlvera-Montaño Cecilia0Castellanos-González José Alberto1Navarro-Partida José2Cardona-Muñoz Ernesto Germán3López-Contreras Ana Karen4Roman-Pintos Luis Miguel5Robles-Rivera Ricardo Raúl6Rodríguez-Carrizalez Adolfo Daniel7Institute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoDepartment of Ophthalmology, Specialties Hospital of the National Occidental Medical Center, Mexican Institute of Social Security, MexicoTecnológico de Monterrey Institute, School of Medicine and Health Sciences, Campus Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoDepartment of Physiology, University Center of Tonalá, University of Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoInstitute of Clinical and Experimental Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, MexicoDiabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset.http://dx.doi.org/10.1155/2019/8562408
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Olvera-Montaño Cecilia Castellanos-González José Alberto Navarro-Partida José Cardona-Muñoz Ernesto Germán López-Contreras Ana Karen Roman-Pintos Luis Miguel Robles-Rivera Ricardo Raúl Rodríguez-Carrizalez Adolfo Daniel
spellingShingle	Olvera-Montaño Cecilia Castellanos-González José Alberto Navarro-Partida José Cardona-Muñoz Ernesto Germán López-Contreras Ana Karen Roman-Pintos Luis Miguel Robles-Rivera Ricardo Raúl Rodríguez-Carrizalez Adolfo Daniel Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology Journal of Diabetes Research
author_facet	Olvera-Montaño Cecilia Castellanos-González José Alberto Navarro-Partida José Cardona-Muñoz Ernesto Germán López-Contreras Ana Karen Roman-Pintos Luis Miguel Robles-Rivera Ricardo Raúl Rodríguez-Carrizalez Adolfo Daniel
author_sort	Olvera-Montaño Cecilia
title	Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
title_short	Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
title_full	Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
title_fullStr	Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
title_full_unstemmed	Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology
title_sort	oxidative stress as the main target in diabetic retinopathy pathophysiology
publisher	Hindawi Limited
series	Journal of Diabetes Research
issn	2314-6745 2314-6753
publishDate	2019-01-01
description	Diabetic retinopathy (DR) is one of the most common complications of diabetes mellitus (DM) causing vision impairment even at young ages. There are numerous mechanisms involved in its development such as inflammation and cellular degeneration leading to endothelial and neural damage. These mechanisms are interlinked thus worsening the diabetic retinopathy outcome. In this review, we propose oxidative stress as the focus point of this complication onset.
url	http://dx.doi.org/10.1155/2019/8562408
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Oxidative Stress as the Main Target in Diabetic Retinopathy Pathophysiology

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