The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction.

The proline-rich motif of the proDer p 3 allergen propeptide is crucial for protease-protease interaction.

The majority of proteases are synthesized in an inactive form, termed zymogen, which consists of a propeptide and a protease domain. The propeptide is commonly involved in the correct folding and specific inhibition of the enzyme. The propeptide of the house dust mite allergen Der p 3, NPILPASPNAT,...

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Bibliographic Details
Main Authors: Marie-Eve Dumez, Julie Herman, Vincenzo Campisi, Ahlem Bouaziz, Frédéric Rosu, André Luxen, Isabel Vandenberghe, Edwin de Pauw, Jean-Marie Frère, André Matagne, Andy Chevigné, Moreno Galleni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3779199?pdf=render

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