Genetics, epigenetics and redox homeostasis in rhabdomyosarcoma: Emerging targets and therapeutics
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma accounting for 5–8% of malignant tumours in children and adolescents. Children with high risk disease have poor prognosis. Anti-RMS therapies include surgery, radiation and combination chemotherapy. While these strategies improved surviva...
Main Authors: | Ananya Pal, Hsin Yao Chiu, Reshma Taneja |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2019-07-01
|
Series: | Redox Biology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231718311406 |
Similar Items
-
EHMT2 epigenetically suppresses Wnt signaling and is a potential target in embryonal rhabdomyosarcoma
by: Ananya Pal, et al.
Published: (2020-11-01) -
Exercise, redox homeostasis and the epigenetic landscape
by: Ivan Dimauro, et al.
Published: (2020-08-01) -
Redox Homeostasis and Prospects for Therapeutic Targeting in Neurodegenerative Disorders
by: Musbau Adewumi Akanji, et al.
Published: (2021-01-01) -
Epigenetics in rhabdomyosarcoma: cues to new biomarkers and targeted therapies
by: Francesca Megiorni
Published: (2020-02-01) -
Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target
by: Cara E. Shields, et al.
Published: (2021-08-01)