Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period

Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period

To characterize methicillin-resistant Staphylococcus aureus isolates from an intensive care unit of a tertiary-care teaching hospital, between 2005 and 2010. A total of 45 isolates were recovered from patients admitted to the intensive care unit in the study period. Resistance rates higher than 80%...

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Main Authors: Thiago C. Nascimento, Cláudio G. Diniz, Vânia L. Silva, Alessandra B. Ferreira-Machado, Marina O. Fajardo, Tamara Lopes R. de Oliveira, Dennis de C. Ferreira, Fernanda S. Cavalcante, Kátia R. Netto dos Santos
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867017307742
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spelling doaj-379a48d8dfa24c2c8c74bb0951f910722020-11-25T02:58:34ZengElsevierBrazilian Journal of Infectious Diseases1413-86702018-01-012215559Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year periodThiago C. Nascimento0Cláudio G. Diniz1Vânia L. Silva2Alessandra B. Ferreira-Machado3Marina O. Fajardo4Tamara Lopes R. de Oliveira5Dennis de C. Ferreira6Fernanda S. Cavalcante7Kátia R. Netto dos Santos8Universidade Federal de Juiz de Fora, Departamento de Parasitologia, Microbiologia e Imunologia, Juiz de Fora, MG, BrazilUniversidade Federal de Juiz de Fora, Departamento de Parasitologia, Microbiologia e Imunologia, Juiz de Fora, MG, BrazilUniversidade Federal de Juiz de Fora, Departamento de Parasitologia, Microbiologia e Imunologia, Juiz de Fora, MG, BrazilUniversidade Federal do Triângulo Mineiro, Departamento de Microbiologia, Imunologia e Parasitologia, Uberaba, MG, BrazilUniversidade Federal de Juiz de Fora, Departamento de Parasitologia, Microbiologia e Imunologia, Juiz de Fora, MG, BrazilUniversidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Rio de Janeiro, RJ, BrazilUniversidade Veiga de Almeida, Rio de Janeiro, RJ, Brazil; Universidade Estácio de Sá, Rio de Janeiro, RJ, BrazilUniversidade Federal do Rio de Janeiro, Macaé, RJ, BrazilUniversidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Rio de Janeiro, RJ, Brazil; Corresponding author.To characterize methicillin-resistant Staphylococcus aureus isolates from an intensive care unit of a tertiary-care teaching hospital, between 2005 and 2010. A total of 45 isolates were recovered from patients admitted to the intensive care unit in the study period. Resistance rates higher than 80% were found for clindamycin (100%), erythromycin (100%), levofloxacin (100%), azithromycin (97.7%), rifampin (88.8%), and gentamycin (86.6%). The SCCmec typing revealed that the isolates harbored the types III (66.7%), II (17.8%), IV (4.4%), and I (2.2%). Four (8.9%) isolates carried non-typeable cassettes. Most (66.7%) of the isolates were related to the Brazilian endemic clone from CC8/SCCmec III, which was prevalent (89.3%) between 2005 and 2007, while the USA100/CC5/SCCmec II lineage emerged in 2007 and was more frequent in the last few years. The study showed high rates of antimicrobial resistance among methicillin-resistant S. aureus isolates and the replacement of Brazilian clone, a well-established hospital lineage, by the USA100 in the late 2000s, at the intensive care unit under study. Keywords: Clonal complex, MRSA, PFGE lineages, SCCmechttp://www.sciencedirect.com/science/article/pii/S1413867017307742
collection DOAJ
language English
format Article
sources DOAJ
author Thiago C. Nascimento
Cláudio G. Diniz
Vânia L. Silva
Alessandra B. Ferreira-Machado
Marina O. Fajardo
Tamara Lopes R. de Oliveira
Dennis de C. Ferreira
Fernanda S. Cavalcante
Kátia R. Netto dos Santos
spellingShingle Thiago C. Nascimento
Cláudio G. Diniz
Vânia L. Silva
Alessandra B. Ferreira-Machado
Marina O. Fajardo
Tamara Lopes R. de Oliveira
Dennis de C. Ferreira
Fernanda S. Cavalcante
Kátia R. Netto dos Santos
Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period
Brazilian Journal of Infectious Diseases
author_facet Thiago C. Nascimento
Cláudio G. Diniz
Vânia L. Silva
Alessandra B. Ferreira-Machado
Marina O. Fajardo
Tamara Lopes R. de Oliveira
Dennis de C. Ferreira
Fernanda S. Cavalcante
Kátia R. Netto dos Santos
author_sort Thiago C. Nascimento
title Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period
title_short Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period
title_full Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period
title_fullStr Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period
title_full_unstemmed Methicillin-resistant Staphylococcus aureus isolated from an intensive care unit in Minas Gerais, Brazil, over a six-year period
title_sort methicillin-resistant staphylococcus aureus isolated from an intensive care unit in minas gerais, brazil, over a six-year period
publisher Elsevier
series Brazilian Journal of Infectious Diseases
issn 1413-8670
publishDate 2018-01-01
description To characterize methicillin-resistant Staphylococcus aureus isolates from an intensive care unit of a tertiary-care teaching hospital, between 2005 and 2010. A total of 45 isolates were recovered from patients admitted to the intensive care unit in the study period. Resistance rates higher than 80% were found for clindamycin (100%), erythromycin (100%), levofloxacin (100%), azithromycin (97.7%), rifampin (88.8%), and gentamycin (86.6%). The SCCmec typing revealed that the isolates harbored the types III (66.7%), II (17.8%), IV (4.4%), and I (2.2%). Four (8.9%) isolates carried non-typeable cassettes. Most (66.7%) of the isolates were related to the Brazilian endemic clone from CC8/SCCmec III, which was prevalent (89.3%) between 2005 and 2007, while the USA100/CC5/SCCmec II lineage emerged in 2007 and was more frequent in the last few years. The study showed high rates of antimicrobial resistance among methicillin-resistant S. aureus isolates and the replacement of Brazilian clone, a well-established hospital lineage, by the USA100 in the late 2000s, at the intensive care unit under study. Keywords: Clonal complex, MRSA, PFGE lineages, SCCmec
url http://www.sciencedirect.com/science/article/pii/S1413867017307742
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