Genetic contribution to mesenchymal stem cell dysfunction in systemic lupus erythematosus

Genetic contribution to mesenchymal stem cell dysfunction in systemic lupus erythematosus

Abstract Allogeneic mesenchymal stem cell (MSC) transplantation has recently become a promising therapy for patients with systemic lupus erythematosus (SLE). MSCs are a kind of multipotent stem cell than can efficiently modulate both innate and adaptive immune responses, yet those from SLE patients...

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Bibliographic Details
Main Authors: Yantong Zhu, Xuebing Feng
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Stem Cell Research & Therapy
Subjects:
Systemic lupus erythematosus
Mesenchymal stem cells
Genetic factors
Online Access:http://link.springer.com/article/10.1186/s13287-018-0898-x

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