Crystal structure of the S. solfataricus archaeal exosome reveals conformational flexibility in the RNA-binding ring.

The exosome complex is an essential RNA 3'-end processing and degradation machinery. In archaeal organisms, the exosome consists of a catalytic ring and an RNA-binding ring, both of which were previously reported to assume three-fold symmetry.Here we report an asymmetric 2.9 A Sulfolobus solfat...

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Bibliographic Details
Main Authors: Changrui Lu, Fang Ding, Ailong Ke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2806925?pdf=render