Dramatic increase in lever-pressing activity in rats after training on the progressive ratio schedule of cocaine self-administration

Abstract Transition from the highest rate of lever-pressing activity during the unloading (extinction) phase of a cocaine self-administration session to an extremely low activity rate during the remission phase is in many cases gradual. This makes it difficult to assess the duration of the unloading...

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Bibliographic Details
Main Authors: Vladimir L. Tsibulsky, Andrew B. Norman
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98313-0