Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma
Abstract Metastasis is present in approximately 30% of patients diagnosed with renal cell carcinoma (RCC) and is associated with a 5-year survival rate of < 15%. Kidney injury molecule 1 (KIM-1), encoded by the HAVCR1 gene, is a proximal tubule cell-surface glycoprotein and a biomarker for early...
Main Authors: | Jasper C. Lee, Demitra M. Yotis, Ji Yun Lee, Marie A. Sarabusky, Bradly Shrum, Audrey Champagne, Ola Z. Ismail, Elena Tutunea-Fatan, Hon S. Leong, Lakshman Gunaratnam |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-06-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-90919-8 |
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