Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma

Abstract Metastasis is present in approximately 30% of patients diagnosed with renal cell carcinoma (RCC) and is associated with a 5-year survival rate of < 15%. Kidney injury molecule 1 (KIM-1), encoded by the HAVCR1 gene, is a proximal tubule cell-surface glycoprotein and a biomarker for early...

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Bibliographic Details
Main Authors: Jasper C. Lee, Demitra M. Yotis, Ji Yun Lee, Marie A. Sarabusky, Bradly Shrum, Audrey Champagne, Ola Z. Ismail, Elena Tutunea-Fatan, Hon S. Leong, Lakshman Gunaratnam
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-90919-8

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