Potential in vitro model for testing the effect of exposure to nanoparticles on the lung alveolar epithelial barrier

Potential in vitro model for testing the effect of exposure to nanoparticles on the lung alveolar epithelial barrier

Pulmonary barrier function plays a pivotal role in protection from inhaled particles. However, some nano-scaled particles, such as carbon nanotubes (CNT), have demonstrated the ability to penetrate this barrier in animal models, resulting in an unusual, rapid interstitial fibrosis. To delineate the...

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Bibliographic Details
Main Authors: Raymond Derk, Donna C. Davidson, Amruta Manke, Todd A. Stueckle, Yon Rojanasakul, Liying Wang
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Sensing and Bio-Sensing Research
Subjects:
Nanoparticles
Lung
In vitro model
Pulmonary barrier
Toxicology
Online Access:http://www.sciencedirect.com/science/article/pii/S2214180414000439

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