Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population

BACKGROUND: HIV-1 is a highly diverse virus; subtypes may exhibit differences in rates of transmission, disease progression, neurotoxicity, antiretroviral treatment failure profiles and accuracy of viral load measurements. To date, the HIV epidemic in Canada and the rest of the developed world has b...

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Main Authors: Reed AC Siemieniuk, Brenda Beckthold, M John Gill
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2013/230380
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spelling doaj-3766373a9a1d410980caa18eb9ddf9462021-07-02T03:52:56ZengHindawi LimitedCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322013-01-01242697310.1155/2013/230380Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American PopulationReed AC Siemieniuk0Brenda Beckthold1M John Gill2Southern Alberta HIV Clinic, Calgary, Alberta, CanadaSouthern Alberta HIV Clinic, Calgary, Alberta, CanadaSouthern Alberta HIV Clinic, Calgary, Alberta, CanadaBACKGROUND: HIV-1 is a highly diverse virus; subtypes may exhibit differences in rates of transmission, disease progression, neurotoxicity, antiretroviral treatment failure profiles and accuracy of viral load measurements. To date, the HIV epidemic in Canada and the rest of the developed world has been largely due to subtype B; however, shifts in subtype epidemiology could have significant implications.http://dx.doi.org/10.1155/2013/230380
collection DOAJ
language English
format Article
sources DOAJ
author Reed AC Siemieniuk
Brenda Beckthold
M John Gill
spellingShingle Reed AC Siemieniuk
Brenda Beckthold
M John Gill
Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population
Canadian Journal of Infectious Diseases and Medical Microbiology
author_facet Reed AC Siemieniuk
Brenda Beckthold
M John Gill
author_sort Reed AC Siemieniuk
title Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population
title_short Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population
title_full Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population
title_fullStr Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population
title_full_unstemmed Increasing HIV Subtype Diversity and Its Clinical Implications in a Sentinel North American Population
title_sort increasing hiv subtype diversity and its clinical implications in a sentinel north american population
publisher Hindawi Limited
series Canadian Journal of Infectious Diseases and Medical Microbiology
issn 1712-9532
publishDate 2013-01-01
description BACKGROUND: HIV-1 is a highly diverse virus; subtypes may exhibit differences in rates of transmission, disease progression, neurotoxicity, antiretroviral treatment failure profiles and accuracy of viral load measurements. To date, the HIV epidemic in Canada and the rest of the developed world has been largely due to subtype B; however, shifts in subtype epidemiology could have significant implications.
url http://dx.doi.org/10.1155/2013/230380
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