Omics-Based Identification of Shared and Gender Disparity Routes in Hras12V-Induced Hepatocarcinogenesis: An Important Role for Dlk1-Dio3 Genomic Imprinting Region

Omics-Based Identification of Shared and Gender Disparity Routes in Hras12V-Induced Hepatocarcinogenesis: An Important Role for Dlk1-Dio3 Genomic Imprinting Region

The phenomenon of gender disparity is very profound in hepatocellular carcinoma (HCC). Although previous research has revealed important roles of microRNA (miRNA) in HCC, there are no studies investigating the role of miRNAs in gender disparity observed hepatocarcinogenesis. In the present study, we...

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Bibliographic Details
Main Authors: Jing Zhang, Huiling Li, Jianyi Dong, Nan Zhang, Yang Liu, Xiaoqin Luo, Jun Chen, Jingyu Wang, Aiguo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
miRNAomics
hepatocarcinogenesis
gender disparity
Dlk1-Dio3 genomic imprinting region
Hras12V-transgenic mice
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.620594/full

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