Recent progress on lanthanide scintillators for soft X‐ray‐triggered bioimaging and deep‐tissue theranostics

Abstract Lanthanide scintillators capable of converting the absorbed X‐ray photon energy to ultraviolet (UV) or visible light, are emerged as promising nanoprobes for multifunctional diagnosis and deep‐tissue antitumor therapy such as X‐ray‐excited fluorescence (XEF) imaging, X‐ray‐triggered photody...

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Bibliographic Details
Main Authors: Mingyang Jiang, Zhiming Deng, Songjun Zeng, Jianhua Hao
Format: Article
Language:English
Published: Wiley 2021-08-01
Series:View
Online Access:https://doi.org/10.1002/VIW.20200122
Description
Summary:Abstract Lanthanide scintillators capable of converting the absorbed X‐ray photon energy to ultraviolet (UV) or visible light, are emerged as promising nanoprobes for multifunctional diagnosis and deep‐tissue antitumor therapy such as X‐ray‐excited fluorescence (XEF) imaging, X‐ray‐triggered photodynamic therapy (X‐PDT), and soft X‐ray‐activated NO gas therapy. Such biomedical tools have the potential to overcome the major challenge of the depth barrier suffered by traditional optics. Recently, various lanthanide scintillators have been designed for diagnosis and therapy of deep‐seated tumors. This minireview presents an overview of recent progress on the lanthanide‐based scintillators and illustration of the potential challenges and future development.
ISSN:2688-3988
2688-268X