Exploring the binding interactions of structurally diverse dichalcogenoimidodiphosphinate ligands with α-amylase: Spectroscopic approach coupled with molecular docking

Exploring the binding interactions of structurally diverse dichalcogenoimidodiphosphinate ligands with α-amylase: Spectroscopic approach coupled with molecular docking

Postprandial hyperglycemia has orchestrated untimely death among diabetic patients over the decades and regulation of α-amylase activity is now becoming a promising management option for type 2 diabetes. The present study investigated the binding interactions of three structurally diverse dichalcoge...

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Bibliographic Details
Main Authors: Oghenetega J. Avwioroko, Temidayo T. Oyetunde, Francis O. Atanu, Chiagoziem A. Otuechere, Akpovwehwee A. Anigboro, Oluropo F. Dairo, Akpoyovware S. Ejoh, Sunday O. Ajibade, Martins O. Omorogie
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
α-Amylase inhibition
Ligand-protein binding
Spectroscopy
Hyperglycemia
Anti-diabetic agents
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580820301473

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