Interaction of Macrophages and Cholesterol-Dependent Cytolysins: The Impact on Immune Response and Cellular Survival

Cholesterol-dependent cytolysins (CDCs) are key virulence factors involved in many lethal bacterial infections, including pneumonia, necrotizing soft tissue infections, bacterial meningitis, and miscarriage. Host responses to these diseases involve myeloid cells, especially macrophages. Macrophages...

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Bibliographic Details
Main Authors: Roshan Thapa, Sucharit Ray, Peter A. Keyel
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/9/531