Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area.

Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area.

BACKGROUND: Recent interferon gamma (IFN-γ)-based studies have identified novel Mycobacterium tuberculosis (M.tb) infection phase-dependent antigens as diagnostic candidates. In this study, the levels of 11 host markers other than IFN-γ, were evaluated in whole blood culture supernatants after stimu...

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Bibliographic Details
Main Authors: Novel N Chegou, Paulin N Essone, Andre G Loxton, Kim Stanley, Gillian F Black, Gian D van der Spuy, Paul D van Helden, Kees L Franken, Shreemanta K Parida, Michel R Klein, Stefan H E Kaufmann, Tom H M Ottenhoff, Gerhard Walzl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3367928?pdf=render

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http://europepmc.org/articles/PMC3367928?pdf=render

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