Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated Hemolysis

Gangliosides Block Aggregatibacter Actinomycetemcomitans Leukotoxin (LtxA)-Mediated Hemolysis

Aggregatibacter actinomycetemcomitans is an oral pathogen and etiologic agent of localized aggressive periodontitis. The bacterium is also a cardiovascular pathogen causing infective endocarditis. A. actinomycetemcomitans produces leukotoxin (LtxA), an important virulence factor that targets white b...

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Bibliographic Details
Main Authors: Scott C. Kachlany, Nataliya V. Balashova, Rebecca K. Han, Amy Le, Jason B. Nishikubo, Michael S. Forman
Format: Article
Language:English
Published: MDPI AG 2010-12-01
Series:Toxins
Subjects:
erythrocytes
toxin
periodontal disease
endocarditis
RTX toxin
Online Access:http://www.mdpi.com/2072-6651/2/12/2824/

Internet

http://www.mdpi.com/2072-6651/2/12/2824/

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