Osteoblast suppression in multiple myeloma bone disease
Multiple myeloma (MM) is the most frequent cancer to involve the skeleton with patients developing osteolytic bone lesions due to hyperactivation of osteoclasts and suppression of BMSCs differentiation into functional osteoblasts. Although new therapies for MM have greatly improved survival, MM rema...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-11-01
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Series: | Journal of Bone Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2212137418301106 |