Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 Signaling Pathways

Polysaccharides From Chrysanthemum morifolium Ramat Ameliorate Colitis Rats via Regulation of the Metabolic Profiling and NF-κ B/TLR4 and IL-6/JAK2/STAT3 Signaling Pathways

Studies have indicated that Chrysanthemum polysaccharides (CP) could prominently ameliorate colitis rats, but its possible mechanism remains unclear. In this study, the underlying mechanism of CP was explored by the metabolic profiling analysis and correlated signaling pathways. TNBS/ethanol induced...

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Bibliographic Details
Main Authors: Jin-Hua Tao, Jin-Ao Duan, Wei Zhang, Shu Jiang, Jian-Ming Guo, Dan-Dan Wei
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Pharmacology
Subjects:
Chrysanthemum polysaccharides
colitis
metabonomics
signaling pathway
IBD
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00746/full

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