Accessibility to Peptidoglycan Is Important for the Recognition of Gram-Positive Bacteria in Drosophila
Summary: In Drosophila, it is thought that peptidoglycan recognition proteins (PGRPs) SA and LC structurally discriminate between bacterial peptidoglycans with lysine (Lys) or diaminopimelic (DAP) acid, respectively, thus inducing differential antimicrobial transcription response. Here, we find that...
Main Authors: | Filipa Vaz, Ilias Kounatidis, Gonçalo Covas, Richard M. Parton, Maria Harkiolaki, Ilan Davis, Sergio Raposo Filipe, Petros Ligoxygakis |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-05-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719305832 |
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