Accessibility to Peptidoglycan Is Important for the Recognition of Gram-Positive Bacteria in Drosophila

Summary: In Drosophila, it is thought that peptidoglycan recognition proteins (PGRPs) SA and LC structurally discriminate between bacterial peptidoglycans with lysine (Lys) or diaminopimelic (DAP) acid, respectively, thus inducing differential antimicrobial transcription response. Here, we find that...

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Bibliographic Details
Main Authors: Filipa Vaz, Ilias Kounatidis, Gonçalo Covas, Richard M. Parton, Maria Harkiolaki, Ilan Davis, Sergio Raposo Filipe, Petros Ligoxygakis
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719305832