Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline
Drugs for the drug-resistant bacterial strains constitute one of the most essential challenges for medicine now-a-days. Seven derivatives of thiadiazolo[2′,3′:2,3]imidazo [4,5-b]quinoxalines were synthesized for potential antimicrobial agents. The structures of the compounds were established by IR,...
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2016-09-01
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| Series: | Journal of Saudi Chemical Society |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610312002001 |
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doaj-37027e6b97dc420b90e58259e2dfd2812020-11-24T22:57:11ZengElsevierJournal of Saudi Chemical Society1319-61032016-09-0120S1S387S39210.1016/j.jscs.2012.12.011Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxalineRamakrishna Teja0Sivakrishna Kapu1Swapana Kadiyala2Visagaperumal Dhanapal3Anbalagan Navaneetha Raman4Bapatla College of Pharmacy, Department of Pharmacy, Acharya Nagarjuna University, Guntur, Andhrapradesh, IndiaBapatla College of Pharmacy, Department of Pharmacy, Acharya Nagarjuna University, Guntur, Andhrapradesh, IndiaBapatla College of Pharmacy, Department of Pharmacy, Acharya Nagarjuna University, Guntur, Andhrapradesh, IndiaBapatla College of Pharmacy, Department of Pharmacy, Acharya Nagarjuna University, Guntur, Andhrapradesh, IndiaPydah College of Pharmacy, Kakinada, Andhrapradesh, IndiaDrugs for the drug-resistant bacterial strains constitute one of the most essential challenges for medicine now-a-days. Seven derivatives of thiadiazolo[2′,3′:2,3]imidazo [4,5-b]quinoxalines were synthesized for potential antimicrobial agents. The structures of the compounds were established by IR, 1H NMR, mass spectral and elemental analysis. The anti-microbial evaluation of the newly synthesized products against a broad spectrum of bacteria was performed using the disc diffusion technique and the agar streak dilution method. All the synthesized compounds had shown good inhibitory effect.http://www.sciencedirect.com/science/article/pii/S1319610312002001NitroquinoxalineThiadiazoleAntibacterialAntifungal |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Ramakrishna Teja Sivakrishna Kapu Swapana Kadiyala Visagaperumal Dhanapal Anbalagan Navaneetha Raman |
| spellingShingle |
Ramakrishna Teja Sivakrishna Kapu Swapana Kadiyala Visagaperumal Dhanapal Anbalagan Navaneetha Raman Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline Journal of Saudi Chemical Society Nitroquinoxaline Thiadiazole Antibacterial Antifungal |
| author_facet |
Ramakrishna Teja Sivakrishna Kapu Swapana Kadiyala Visagaperumal Dhanapal Anbalagan Navaneetha Raman |
| author_sort |
Ramakrishna Teja |
| title |
Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline |
| title_short |
Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline |
| title_full |
Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline |
| title_fullStr |
Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline |
| title_full_unstemmed |
Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline |
| title_sort |
heterocyclic systems containing bridgehead nitrogen atom: synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-b]quinoxaline |
| publisher |
Elsevier |
| series |
Journal of Saudi Chemical Society |
| issn |
1319-6103 |
| publishDate |
2016-09-01 |
| description |
Drugs for the drug-resistant bacterial strains constitute one of the most essential challenges for medicine now-a-days. Seven derivatives of thiadiazolo[2′,3′:2,3]imidazo [4,5-b]quinoxalines were synthesized for potential antimicrobial agents. The structures of the compounds were established by IR, 1H NMR, mass spectral and elemental analysis. The anti-microbial evaluation of the newly synthesized products against a broad spectrum of bacteria was performed using the disc diffusion technique and the agar streak dilution method. All the synthesized compounds had shown good inhibitory effect. |
| topic |
Nitroquinoxaline Thiadiazole Antibacterial Antifungal |
| url |
http://www.sciencedirect.com/science/article/pii/S1319610312002001 |
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