Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline

Heterocyclic systems containing bridgehead nitrogen atom: Synthesis and antimicrobial activity of thiadiazolo[2′,3′:2,3]imidazo[4,5-B]quinoxaline

Drugs for the drug-resistant bacterial strains constitute one of the most essential challenges for medicine now-a-days. Seven derivatives of thiadiazolo[2′,3′:2,3]imidazo [4,5-b]quinoxalines were synthesized for potential antimicrobial agents. The structures of the compounds were established by IR,...

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Bibliographic Details
Main Authors: Ramakrishna Teja, Sivakrishna Kapu, Swapana Kadiyala, Visagaperumal Dhanapal, Anbalagan Navaneetha Raman
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Saudi Chemical Society
Subjects:
Nitroquinoxaline
Thiadiazole
Antibacterial
Antifungal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610312002001
Description
Summary:Drugs for the drug-resistant bacterial strains constitute one of the most essential challenges for medicine now-a-days. Seven derivatives of thiadiazolo[2′,3′:2,3]imidazo [4,5-b]quinoxalines were synthesized for potential antimicrobial agents. The structures of the compounds were established by IR, 1H NMR, mass spectral and elemental analysis. The anti-microbial evaluation of the newly synthesized products against a broad spectrum of bacteria was performed using the disc diffusion technique and the agar streak dilution method. All the synthesized compounds had shown good inhibitory effect.
ISSN:1319-6103

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