Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5‐diamino‐6‐chloro‐N‐(N‐(2,6‐dichlorobenzoyl)carbamimidoyl)pyrazine‐2‐carboxide

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5‐diamino‐6‐chloro‐N‐(N‐(2,6‐dichlorobenzoyl)carbamimidoyl)pyrazine‐2‐carboxide

Alternative splicing (AS) is a process that enables the generation of multiple protein isoforms with different biological properties from a single mRNA. Cancer cells often use the maneuverability conferred by AS to produce proteins that contribute to growth and survival. In our previous studies, we...

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Bibliographic Details
Main Authors: Chien‐Chin Lee, Wen‐Hsin Chang, Ya‐Sian Chang, Jinn‐Moon Yang, Chih‐Shiang Chang, Kai‐Cheng Hsu, Yun‐Ti Chen, Ting‐Yuan Liu, Yu‐Chia Chen, Shyr‐Yi Lin, Yang‐Chang Wu, Jan‐Gowth Chang
Format: Article
Language:English
Published: Wiley 2019-08-01
Series:Molecular Oncology
Subjects:
alternative splicing
amiloride
apoptosis
cancer
sorafenib
Online Access:https://doi.org/10.1002/1878-0261.12524

Internet

https://doi.org/10.1002/1878-0261.12524

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